Feline polymorphonuclear neutrophils produce pro-inflammatory cytokines following exposure to Microsporum canis

Dermatophytosis, Microsporum canis, Trichophyton mentagrophytes, Microsporum gypseum

Overview: The fungal skin disease dermatophytosis has come to be called ringworm because of the appearance of the skin lesion that characteristically occurs with this disorder: a circular area of hair loss with a red, raised outer rim. These lesions result from an inflammatory reaction to the fungus. Most often, dogs and cats are infected by the Microsporum canis fungus, but other types of fung...

Carbohydrate metabolism in Microsporum canis.

Enzyme systems concerned in the breakdown of carbohydrates by dennatophytes have been little studied, the principal contribution being a study of a number of enzymes of the glycolytic and hexosemonophosphate pathways and of the tricarboxylic acid cycle in cell-free extracts of Trichophyton mentagrophytes (Jensen, Altschuller & Bard, 1957). The effect of different substrates and pH values on the...

Pro-inflammatory cytokines in atherosclerosis.

The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines.

Childhood chronic inflammatory disease can be associated with transient and permanent growth retardation. This study examined the potential for spontaneous growth recovery following pro-inflammatory cytokine exposure. Murine ATDC5 chondrogenic cells and postnatal metatarsals were exposed to interleukin (IL)-1beta, IL-6 and tumour necrosis factor-alpha (TNFalpha), and their growth and proliferat...

Changes in pro-inflammatory cytokines in association with exposure to moisture-damaged building microbes.

Several epidemiological studies have described an association between adverse health effects and exposure to mould and microbes present in the indoor air of moisture-damaged buildings. However, the biochemical linkage between microbial exposure and the large variety of reported respiratory symptoms is poorly understood. In the present study, the authors compared the respiratory symptoms, the pr...